UNIZ LAB · Core Technology

Proprietary Enzyme-Based
Spicule Refinement Technology

Using proprietary low-temperature enzyme treatment technology, we preserve the bioactive components of SPICULE to the maximum and produce raw materials with high purity.

4°C Low Temperature
Process Temperature
72+ Hours
Treatment Time
99%+
Purity
Why Enzyme Treatment

Chemical Extraction vs. Enzyme Treatment

UNIZ LAB uses natural enzyme enzyme treatment instead of harmful chemical solvents for extraction

Comparison ItemConventional Chemical Extraction (HCl)UNIZ LAB Enzyme Treatment
Solvent✕Strong acids such as hydrochloric acid (HCl)✓Natural enzyme culture medium
Temperature✕High-temperature processing (80–120°C)✓4°C Low-temperature enzyme treatment
Active Components✕30%+ loss from thermal decomposition✓99% component retention
Residual Solvent✕Solvent residue inside spicule cylinder → formulation breakdown after 2~3 months✓Zero residual solvent (ND) → long-term formulation stability
Environment✕Hazardous wastewater generation✓Zero chemical solvents, eco-friendly
Purity✕85~95%✓99% or higher
Process Pipeline

4-Step Enzyme Treatment & Extraction Process

All stages comply with ISO standards

01

Raw Material Pretreatment

Harvested sponges are precision-cleaned and separated to completely remove foreign materials.

02

Low-Temperature Enzyme Treatment Initiation

Proprietary protease enzyme solution is introduced at 4°C to begin enzyme treatment.

03

72-Hour Treatment Monitoring

pH, temperature, and activity are monitored in real-time over 72 hours.

04

Extraction and Purification

Supercritical extraction separates and purifies bioactive components without loss.

Key Advantages

Key Advantages of Enzyme Treatment

Eco-Friendly Process

100% biological extraction process with zero chemical solvents. No hazardous wastewater generation.

Active Component Retention

Low-temperature enzyme treatment preserves 99% or more of heat-sensitive bioactive components.

High Purity Achievement

Combined with 23-stage purification process to produce high-purity raw materials with less than 0.2% impurities.

Reproducibility Assurance

Standardized enzyme treatment protocol minimizes quality variance between batches.

Technology License Inquiry

We welcome inquiries regarding technology transfer and collaborative research on enzyme treatment technology.