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HA Sphere Spicule

HA Sphere
Spicule

The fusion of freeze-dried Hyaluronic Acid and 99% high-purity Spicule.
The ultimate skin delivery system that encapsulates Spicule within an HA sphere.

Freeze-Dried HA × Bio-Spicule

Freeze-Dried HA × 99% Spicule
The Ultimate Skin Delivery System

Freeze-drying technology that surpasses the limitations of liquid ampoules meets the Spicule (Bio-Microneedle) that paves a direct path into the skin. Experience the skincare revolution proven by scientific data.

Freeze-Dried HA

Breaking Through the Limits of Freeze-Dried Cosmetics

  • 100% Active Preservation — Removes only moisture at sub-zero temperatures, preserving ingredients vulnerable to heat and water without damage
  • Preservative-Free Safety — An environment where microbes cannot grow — safe for sensitive skin without preservatives
  • Fresh Hydration — Activates instantly upon contact with skin as an ultra-concentrated ampoule by binding with liquid
Spicule Spec

UNIZ LAB Spicule's Distinctive Specifications

  • 99% Ultra-High Purity — 15 years of research and a 23-step eco-friendly refining process completely eliminate impurities
  • 10.59 Million Channels per Gram — Based on 270 µm — tens of millions of microneedles pioneer seamless pathways for active ingredients
  • Precision Ingredient Delivery — A structure that physically assists transdermal delivery of freeze-dried HA and active ingredients through microchannels formed in the stratum corneum
Technology Secret

Spicule's Hidden Secret:
Porous (Hollow) Structure

UNIZ LAB Spicule is not merely a 'solid needle.' This microneedle, based on silicon dioxide (Bio-SiO₂), has an outer diameter of 15 µm and an inner diameter of 1.5 µm,forming a hollow cylindrical tunnel structure.

Freeze-dried HA liquid is Infused into this 1.5 µm micro-cavity and delivered together with the Spicule from the stratum corneum to the lower epidermis. It is as efficient as a sponge holding water and squeezing it into the lower epidermis.
15µm
Outer Diameter
1.5µm
Inner Tunnel (HA Infused)
Synergy Action Mechanism

Spicule + HA Synergy Action Mechanism

Click each step button to view the process of reaching the lower epidermis.

99% high-purity Spicule applied on the skin surface (stratum corneum) forms physical microchannels. Freeze-dried HA is bonded inside the 1.5 µm internal space and on the surface of the Spicule.
Stratum Corneum (S. Corneum)
Epidermis
Basal Layer
Data Evidence

Overwhelming Efficiency Proven by Data

Skin improvement effects of the Spicule TDS (Transdermal Delivery System) based on clinical and research papers

Persistence in Skin

Standard Liquid (24h)5%
Spicule System (24h)88%
Spicule System (72h)50%
72hLong-Lasting Release
Skin Journey Timeline

Skin Transformation Timeline After Use

A remarkable 14-day skin turnover process initiated by a single application

D+1

Penetration and Hydration

Spicule passes through the stratum corneum with a slight tingling sensation. Infused freeze-dried HA is delivered to the lower epidermis, immediately resolving deep dehydration.

D+3

Exfoliation & Turnover

Along with the natural exfoliation cycle, old dead skin cells are naturally cleared away, and the delivered freeze-dried HA fills in deep hydration.

D+7

Deep Hydration & Radiance

Continuous moisture supply smooths skin texture and helps achieve a clear complexion and natural inner glow.

D+14

Barrier Restoration & Firmness

The compromised barrier becomes robust and densely filled. Facial contour firmness improves. Blemish marks and pigmentation are alleviated.

Product Lineup

HA Sphere Spicule Color Lineup

BSPN-HAS-CL

HA Sphere (Clear)

Clear — Standard Type

The most versatile clear type. Naturally harmonizes with any formulation, offering a visually clean finish.

BSPN-HAS-PK

HA Sphere (Pink)

Pink — Tone-Up Effect

Maximizes tone-up effect with pink color. Optimal for premium women's anti-aging lines.

BSPN-HAS-GD

HA Sphere (Gold)

Gold — Premium

Luxurious visual appeal of gold color. A differentiated marketing point for luxury lines / VIP products.

Uncompromised Quality, UNIZ LAB's Promise

Strict quality control by a Spicule raw material supplier, exporting worldwide

23-Step Refining
Eco-friendly Enzymatic Process
ISO Certification
9001 / 22716 Acquired
GAMMA Certification
Gamma irradiation process
P&K Clinical Test
Skin Safety Verified

Academic and Technical References

  • UNIZ LAB R&D Data: 99% high-purity refining, approximately 10.59 million particles per gram (based on 270 µm), Spicule outer diameter (15 µm) and inner diameter (1.5 µm) porous structure.
  • Transdermal Delivery System (TDS): Prausnitz, M. R., & Langer, R. (2008). Transdermal drug delivery. Nature Biotechnology, 26(11), 1261-1268.
  • Transdermal Delivery (Microneedles): Waghule, T., et al. (2019). Microneedles: A smart approach and increasing potential for transdermal drug delivery system. Biomedicine & Pharmacotherapy, 109, 1249-1258.

HA Sphere Spicule Inquiry

We welcome consultations on freeze-dried HA + Spicule complex ingredients. Custom color production available.